STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2LOW QUALITY PROTEIN: SH2B adapter protein 2. (813 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.970
GRB2
Growth factor receptor-bound protein 2 isoform X1.
    
 0.965
INSR
Tyrosine-protein kinase receptor.
    
 0.964
CBLB
E3 ubiquitin-protein ligase CBL-B.
    
 0.955
NTRK3
Tyrosine-protein kinase receptor.
    
 0.929
NTRK2
Tyrosine-protein kinase receptor.
    
 0.925
NTRK1
Tyrosine-protein kinase receptor.
    
 0.924
JAK2
Tyrosine-protein kinase.
   
 0.770
NUDT14
Uridine diphosphate glucose pyrophosphatase.
      
 0.716
PPAP2C
Lipid phosphate phosphohydrolase 2.
      
 0.647
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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