HYAL3 protein (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HYAL3

Hyaluronidase. (419 aa)

Predicted Functional Partners:

GUSB

0.918

ARSB

0.913

IDUA

0.912

ITSN2

0.827

CD44

0.755

ITSN1

0.740

ALB

0.659

INS

0.649

GAK

0.642

ACAN

0.641

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	ALB	A0A2U3ZDN8	A0A2U3VEQ8	LOW QUALITY PROTEIN: aggrecan core protein.	Serum albumin.	0.629
ACAN	CD44	A0A2U3ZDN8	A0A2U3WCC7	LOW QUALITY PROTEIN: aggrecan core protein.	CD44 antigen.	0.589
ACAN	HYAL3	A0A2U3ZDN8	A0A2U3ZEH6	LOW QUALITY PROTEIN: aggrecan core protein.	Hyaluronidase.	0.641
ACAN	INS	A0A2U3ZDN8	A0A2U3W6R9	LOW QUALITY PROTEIN: aggrecan core protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.552
ALB	ACAN	A0A2U3VEQ8	A0A2U3ZDN8	Serum albumin.	LOW QUALITY PROTEIN: aggrecan core protein.	0.629
ALB	CD44	A0A2U3VEQ8	A0A2U3WCC7	Serum albumin.	CD44 antigen.	0.716
ALB	GUSB	A0A2U3VEQ8	A0A2U3WAT7	Serum albumin.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.507
ALB	HYAL3	A0A2U3VEQ8	A0A2U3ZEH6	Serum albumin.	Hyaluronidase.	0.659
ALB	INS	A0A2U3VEQ8	A0A2U3W6R9	Serum albumin.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.928
ARSB	GUSB	A0A2U3WPX0	A0A2U3WAT7	Arylsulfatase B.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.593
ARSB	HYAL3	A0A2U3WPX0	A0A2U3ZEH6	Arylsulfatase B.	Hyaluronidase.	0.913
ARSB	IDUA	A0A2U3WPX0	A0A2U3VMY5	Arylsulfatase B.	alpha-L-iduronidase.	0.951
CD44	ACAN	A0A2U3WCC7	A0A2U3ZDN8	CD44 antigen.	LOW QUALITY PROTEIN: aggrecan core protein.	0.589
CD44	ALB	A0A2U3WCC7	A0A2U3VEQ8	CD44 antigen.	Serum albumin.	0.716
CD44	HYAL3	A0A2U3WCC7	A0A2U3ZEH6	CD44 antigen.	Hyaluronidase.	0.755
CD44	INS	A0A2U3WCC7	A0A2U3W6R9	CD44 antigen.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.618
GAK	HYAL3	A0A2U3VMN0	A0A2U3ZEH6	cyclin-G-associated kinase isoform X1.	Hyaluronidase.	0.642
GAK	ITSN1	A0A2U3VMN0	A0A2U3WCV6	cyclin-G-associated kinase isoform X1.	Intersectin-1 isoform X1.	0.609
GAK	ITSN2	A0A2U3VMN0	A0A2U3ZAA7	cyclin-G-associated kinase isoform X1.	Intersectin-2.	0.745
GUSB	ALB	A0A2U3WAT7	A0A2U3VEQ8	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Serum albumin.	0.507