STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1. (1862 aa)    
Predicted Functional Partners:
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
      
 0.947
ARF4
ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family.
    
 0.934
ARF3
ADP-ribosylation factor 3 isoform X1; Belongs to the small GTPase superfamily. Arf family.
    
 0.920
ARL6
ADP-ribosylation factor-like protein 6 isoform X1; Belongs to the small GTPase superfamily. Arf family.
    
 0.920
ARL1
ADP-ribosylation factor-like protein 1 isoform X1; Belongs to the small GTPase superfamily. Arf family.
    
 0.904
COPA
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
   
 0.888
ARFGAP1
ADP-ribosylation factor GTPase-activating protein 1.
    
 0.842
USO1
General vesicular transport factor p115 isoform X1.
   
 0.824
ARF5
ADP-ribosylation factor 5 isoform X1; Belongs to the small GTPase superfamily. Arf family.
    
 0.822
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.797
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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