node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO1 | AGO2 | A0A2U3W3V7 | A0A2U3ZKX6 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.766 |
AGO1 | DICER1 | A0A2U3W3V7 | A0A2U3VI99 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. | 0.860 |
AGO1 | DROSHA | A0A2U3W3V7 | A0A2U3WR15 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | Ribonuclease 3 isoform X1. | 0.772 |
AGO1 | LOC101366593 | A0A2U3W3V7 | A0A2U3ZKR2 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | LOW QUALITY PROTEIN: protein argonaute-2-like. | 0.766 |
AGO1 | MRPL44 | A0A2U3W3V7 | A0A2U3WFS7 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | 39S ribosomal protein L44, mitochondrial isoform X2. | 0.667 |
AGO1 | STAU2 | A0A2U3W3V7 | A0A2U3ZJ73 | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | Double-stranded RNA-binding protein Staufen homolog 2 isoform X1. | 0.628 |
AGO2 | AGO1 | A0A2U3ZKX6 | A0A2U3W3V7 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-1 isoform X1; Belongs to the argonaute family. | 0.766 |
AGO2 | AGO3 | A0A2U3ZKX6 | A0A2U3W3R9 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.766 |
AGO2 | AGO4 | A0A2U3ZKX6 | A0A2U3W3W1 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.766 |
AGO2 | DICER1 | A0A2U3ZKX6 | A0A2U3VI99 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. | 0.952 |
AGO2 | DROSHA | A0A2U3ZKX6 | A0A2U3WR15 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Ribonuclease 3 isoform X1. | 0.823 |
AGO2 | MRPL44 | A0A2U3ZKX6 | A0A2U3WFS7 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 39S ribosomal protein L44, mitochondrial isoform X2. | 0.667 |
AGO2 | STAU2 | A0A2U3ZKX6 | A0A2U3ZJ73 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Double-stranded RNA-binding protein Staufen homolog 2 isoform X1. | 0.616 |
AGO2 | UPF1 | A0A2U3ZKX6 | A0A2U3W8W2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Regulator of nonsense transcripts 1. | 0.498 |
AGO3 | AGO2 | A0A2U3W3R9 | A0A2U3ZKX6 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.766 |
AGO3 | AGO4 | A0A2U3W3R9 | A0A2U3W3W1 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.417 |
AGO3 | DICER1 | A0A2U3W3R9 | A0A2U3VI99 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. | 0.860 |
AGO3 | DROSHA | A0A2U3W3R9 | A0A2U3WR15 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | Ribonuclease 3 isoform X1. | 0.772 |
AGO3 | LOC101366593 | A0A2U3W3R9 | A0A2U3ZKR2 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | LOW QUALITY PROTEIN: protein argonaute-2-like. | 0.766 |
AGO3 | MRPL44 | A0A2U3W3R9 | A0A2U3WFS7 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 39S ribosomal protein L44, mitochondrial isoform X2. | 0.667 |