STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC1SHC-transforming protein 1 isoform X1. (609 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2 isoform X1.
   
 0.999
SOS1
Son of sevenless homolog 1 isoform X1.
   
 0.991
EGFR
Receptor protein-tyrosine kinase.
    
 0.991
SRC
Tyrosine-protein kinase.
   
0.984
ERBB3
Receptor tyrosine-protein kinase erbB-3.
    
 0.977
ERBB2
Receptor protein-tyrosine kinase.
    
 0.976
SOS2
Son of sevenless homolog 2 isoform X1.
   
 0.975
INSR
Tyrosine-protein kinase receptor.
    
 0.975
IGF1R
Tyrosine-protein kinase receptor.
    
 0.975
TEK
Angiopoietin-1 receptor isoform X1.
   
 0.974
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.