STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF144BRBR-type E3 ubiquitin transferase. (325 aa)    
Predicted Functional Partners:
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 0.668
PRKDC
DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family.
    
 0.654
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.618
UBA52
ubiquitin-60S ribosomal protein L40 isoform X1.
    
  0.617
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 
 0.559
RNF216
E3 ubiquitin-protein ligase RNF216 isoform X1.
    
 0.531
TTC6
Tetratricopeptide repeat protein 6.
      
 0.526
REC114
Meiotic recombination protein REC114.
   
  
 0.525
STXBP6
Syntaxin-binding protein 6.
      
 0.522
BIRC6
Baculoviral IAP repeat-containing protein 6.
    
 0.501
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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