STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (472 aa)    
Predicted Functional Partners:
AQP4
Aquaporin-4 isoform X2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.881
CASP3
Caspase-3 isoform X1; Belongs to the peptidase C14A family.
   
 0.881
CD68
Macrosialin.
   
 
 0.879
MAP2
Microtubule-associated protein.
   
 
 0.871
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
      
 0.870
OLIG2
Oligodendrocyte transcription factor 2.
   
  
 0.858
SYP
Synaptophysin.
   
  
 0.835
IL6
Interleukin-6 isoform X1.
   
  
 0.835
ALDH1L1
10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
      
 0.834
PAX6
Paired box protein Pax-6 isoform X1.
    
 
 0.830
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.