STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRCTyrosine-protein kinase. (553 aa)    
Predicted Functional Partners:
PXN
Paxillin; Belongs to the paxillin family.
   
 0.999
PTK2
Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.999
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.996
STAT3
Signal transducer and activator of transcription.
   
 0.995
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.994
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
  
0.994
EGFR
Receptor protein-tyrosine kinase.
    
0.991
CRK
Adapter molecule crk isoform X1.
   
 0.989
CAV1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
 0.987
GRB2
Growth factor receptor-bound protein 2 isoform X1.
   
0.986
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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