STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICOSLGLOW QUALITY PROTEIN: ICOS ligand. (375 aa)    
Predicted Functional Partners:
ICOS
Inducible T-cell costimulator.
   
 0.999
CTLA4
Cytotoxic T-lymphocyte protein 4 isoform X1.
   
 
 0.936
CD28
T-cell-specific surface glycoprotein CD28.
     
 0.933
CXCR5
C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.544
KLRG2
Killer cell lectin-like receptor subfamily G member 2.
   
 
 0.541
FCGRT
IgG receptor FcRn large subunit p51; Belongs to the MHC class I family.
   
  
 0.531
PUS10
Putative tRNA pseudouridine synthase Pus10 isoform X1.
      
 0.523
PSMG1
Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
   
 
 0.467
TPP2
Tripeptidyl-peptidase 2 isoform X1.
   
 
 0.466
RNF186
LOW QUALITY PROTEIN: RING finger protein 186.
    
 
 0.456
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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