STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)    
Predicted Functional Partners:
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.998
ACAT1
acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.994
HADHB
LOW QUALITY PROTEIN: trifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.993
ACAT2
acetyl-CoA acetyltransferase, cytosolic isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.991
ACAA2
3-ketoacyl-CoA thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.990
ACAA1
3-ketoacyl-CoA thiolase, peroxisomal isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.988
HMGCL
hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1.
     
 0.982
HMGCLL1
LOW QUALITY PROTEIN: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic.
     
 0.972
EHHADH
Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.962
AACS
acetoacetyl-CoA synthetase.
   
 
 0.950
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.