STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MARCH8E3 ubiquitin-protein ligase MARCH8. (569 aa)    
Predicted Functional Partners:
LOC102737789
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1-like.
      
 0.655
PDCD6
Programmed cell death protein 6 isoform X1.
      
 0.633
CNOT2
CCR4-NOT transcription complex subunit 2 isoform X1.
    
 
 0.606
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.561
SAMHD1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.
   
  
 0.550
TUBB1
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
      
 0.546
MARCH5
E3 ubiquitin-protein ligase MARCH5.
   
  
 0.543
BST2
Bone marrow stromal antigen 2.
    
 
 0.534
SERINC3
Serine incorporator 3.
   
  
 0.497
LOC102733072
Myoferlin-like.
      
 0.493
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.