STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL3Achaete-scute homolog 3. (181 aa)    
Predicted Functional Partners:
CCDC153
Coiled-coil domain-containing protein 153.
      
 0.760
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.720
CCDC113
Coiled-coil domain-containing protein 113 isoform X1.
      
 0.702
FOXI1
Forkhead box protein I1 isoform X1.
      
 0.629
LZTFL1
Leucine zipper transcription factor-like protein 1.
      
 0.615
LOC102731354
Lathosterol oxidase-like; Belongs to the sterol desaturase family.
      
 0.499
KRT4
Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family.
      
 0.493
GGACT
Gamma-glutamylaminecyclotransferase.
      
 0.491
ZNF174
Zinc finger protein 174-like isoform X1.
   
 
 0.488
DAPL1
Death-associated protein-like 1.
      
 0.487
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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