STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)    
Predicted Functional Partners:
TSHB
Thyrotropin subunit beta.
    
 0.986
LOC102745211
Follitropin subunit beta-like.
   
 0.930
ADCYAP1
Pituitary adenylate cyclase-activating polypeptide.
     
 0.913
NPPA
Natriuretic peptides A.
   
 
  0.903
GCG
Glucagon isoform X1.
     
 0.899
POMC
Pro-opiomelanocortin.
   
 
 0.838
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
     
 0.821
LOC102739372
Seprase-like.
     
 0.798
GNAL
Guanine nucleotide-binding protein G(Olf) subunit alpha.
    
 0.787
LOC102734642
Guanine nucleotide-binding protein G(Olf) subunit alpha-like.
    
 0.787
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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