STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase. (2072 aa)    
Predicted Functional Partners:
FIG4
Polyphosphoinositide phosphatase.
    
 0.999
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
  
  
 0.952
LOC102747201
Deleted in autism protein 1.
    
 0.946
PI4K2A
Phosphatidylinositol 4-kinase type 2-alpha.
     
 0.937
PI4KB
Phosphatidylinositol 4-kinase beta isoform X2; Belongs to the PI3/PI4-kinase family.
     
 0.933
PI4K2B
Phosphatidylinositol 4-kinase type 2-beta.
     
 0.927
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.914
PIK3C2G
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 
 0.913
PIK3C2B
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.913
PIP4K2B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.
     
0.909
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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