ATP13A4 protein (Leptonychotes weddellii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ATP13A4

Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1197 aa)

Predicted Functional Partners:

MOCOS

0.566

LOC102743809

0.544

DNAJC6

0.532

LOC102731689

0.531

FXYD2

0.530

LOC102746964

0.498

ITGB1BP1

0.493

BHMT

0.483

ZW10

0.482

MFSD6

0.479

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP13A4	BHMT	A0A2U3XRX8	A0A2U3XKD5	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Betaine--homocysteine S-methyltransferase 1 isoform X1; Involved in the regulation of homocysteine metabolism.	0.483
ATP13A4	DNAJC6	A0A2U3XRX8	A0A2U3XXN1	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Putative tyrosine-protein phosphatase auxilin.	0.532
ATP13A4	FXYD2	A0A2U3XRX8	A0A2U3YL01	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.530
ATP13A4	ITGB1BP1	A0A2U3XRX8	A0A2U3Y1K8	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Integrin beta-1-binding protein 1 isoform X1.	0.493
ATP13A4	LOC102731689	A0A2U3XRX8	A0A2U3Y899	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Solute carrier family 13 member 3-like.	0.531
ATP13A4	LOC102743809	A0A2U3XRX8	A0A2U3Z7U1	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.544
ATP13A4	LOC102746964	A0A2U3XRX8	A0A2U3Z4R7	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Sodium/potassium/calcium exchanger 6, mitochondrial-like.	0.498
ATP13A4	MFSD6	A0A2U3XRX8	A0A2U3X6N4	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Major facilitator superfamily domain-containing protein 6.	0.479
ATP13A4	MOCOS	A0A2U3XRX8	A0A2U3YDJ8	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.566
ATP13A4	ZW10	A0A2U3XRX8	A0A2U3XVE2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Centromere/kinetochore protein zw10 homolog.	0.482
BHMT	ATP13A4	A0A2U3XKD5	A0A2U3XRX8	Betaine--homocysteine S-methyltransferase 1 isoform X1; Involved in the regulation of homocysteine metabolism.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.483
BHMT	LOC102731689	A0A2U3XKD5	A0A2U3Y899	Betaine--homocysteine S-methyltransferase 1 isoform X1; Involved in the regulation of homocysteine metabolism.	Solute carrier family 13 member 3-like.	0.548
BHMT	MOCOS	A0A2U3XKD5	A0A2U3YDJ8	Betaine--homocysteine S-methyltransferase 1 isoform X1; Involved in the regulation of homocysteine metabolism.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.928
DNAJC6	ATP13A4	A0A2U3XXN1	A0A2U3XRX8	Putative tyrosine-protein phosphatase auxilin.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.532
FXYD2	ATP13A4	A0A2U3YL01	A0A2U3XRX8	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.530
ITGB1BP1	ATP13A4	A0A2U3Y1K8	A0A2U3XRX8	Integrin beta-1-binding protein 1 isoform X1.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.493
ITGB1BP1	LOC102743809	A0A2U3Y1K8	A0A2U3Z7U1	Integrin beta-1-binding protein 1 isoform X1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.583
ITGB1BP1	ZW10	A0A2U3Y1K8	A0A2U3XVE2	Integrin beta-1-binding protein 1 isoform X1.	Centromere/kinetochore protein zw10 homolog.	0.495
LOC102731689	ATP13A4	A0A2U3Y899	A0A2U3XRX8	Solute carrier family 13 member 3-like.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.531
LOC102731689	BHMT	A0A2U3Y899	A0A2U3XKD5	Solute carrier family 13 member 3-like.	Betaine--homocysteine S-methyltransferase 1 isoform X1; Involved in the regulation of homocysteine metabolism.	0.548