STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC1L1niemann-Pick C1-like protein 1. (1331 aa)    
Predicted Functional Partners:
SREBF2
Sterol regulatory element-binding protein 2-like.
   
 0.926
NPC2
Epididymal secretory protein E1.
   
 0.917
ABCG8
LOW QUALITY PROTEIN: ATP-binding cassette, sub-family G (WHITE), member 8.
   
 
 0.702
OSBPL5
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.645
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
  
 0.547
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.507
FUT1
L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.
      
 0.502
PTPRJ
Receptor-type tyrosine-protein phosphatase eta-like.
    
 
 0.497
MTTP
Microsomal triglyceride transfer protein large subunit.
      
 0.493
CLDN1
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.489
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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