STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DONSONProtein downstream neighbor of Son. (492 aa)    
Predicted Functional Partners:
MRPS6
28S ribosomal protein S6, mitochondrial.
      
 0.811
LOC102730711
DNA replication licensing factor MCM2-like.
   
   0.773
LOC102739679
Lung adenoma susceptibility protein 2 isoform X1.
      
 0.756
LOC102728669
Uncharacterized protein C3orf14 homolog.
      
 0.725
RFC4
Replication factor C subunit 4.
   
  
 0.697
POLD2
DNA polymerase delta subunit 2.
   
  
 0.695
POLR2H
DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1.
   
  
 0.630
FANCM
Fanconi anemia group M protein.
   
  
 0.621
MGME1
Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family.
      
 0.601
DSCC1
Sister chromatid cohesion protein DCC1.
   
  
 0.597
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.