STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX4IPProtein SLX4IP. (408 aa)    
Predicted Functional Partners:
RAD54L2
Helicase ARIP4.
      
 0.769
PCED1A
PC-esterase domain-containing protein 1A isoform X1.
      
 0.580
SLX1A
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
    
 
 0.563
DCLRE1B
5' exonuclease Apollo.
      
 0.545
ANKRD32
Ankyrin repeat domain-containing protein 32 isoform X1.
      
 0.545
LOC102748344
asparagine--tRNA ligase, cytoplasmic-like.
    
 
 0.540
ESF1
ESF1 homolog.
      
 0.493
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
      
 0.493
RHNO1
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1.
      
 0.487
PCSK2
Neuroendocrine convertase 2 isoform X1; Belongs to the peptidase S8 family.
      
 0.485
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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