STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)    
Predicted Functional Partners:
HMG20B
annotation not available
   
 0.982
PHF21A
PHD finger protein 21A-like isoform X1.
    
 0.962
LOC102738770
PHD finger protein 21A-like.
    
 0.962
LOC102745013
Histone H3; Belongs to the histone H3 family.
    
 0.955
RCOR3
REST corepressor 3 isoform X1.
   
 0.949
RCOR2
REST corepressor 2.
   
 0.949
LOC102731039
Histone H3.3-like.
    
 0.942
LOC102732330
Histone H3; Belongs to the histone H3 family.
    
 0.942
LOC102730819
Histone H3; Belongs to the histone H3 family.
    
 0.942
LOC102737083
Histone H3; Belongs to the histone H3 family.
    
 0.935
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (30%) [HD]