STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX42ATP-dependent RNA helicase DDX42. (934 aa)    
Predicted Functional Partners:
LOC102734854
Splicing factor 3B subunit 1-like.
   
 0.998
SF3B5
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
    
 0.985
PHF5A
PHD finger-like domain-containing protein 5A.
    
 0.984
SF3A2
Splicing factor 3A subunit 2.
    
 0.971
SF3B4
Splicing factor 3B subunit 4 isoform X1.
    
 0.963
SF3B2
Splicing factor 3B subunit 2 isoform X1.
   
 0.951
LOC102742014
pre-mRNA branch site protein p14-like.
    
  0.931
DHX15
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15-like.
   
 0.886
RPL35
60S ribosomal protein L35.
   
 
 0.824
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
    
 0.722
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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