STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)    
Predicted Functional Partners:
IL21R
Interleukin-21 receptor.
  
 0.995
LOC102749847
Tyrosine-protein kinase JAK1-like.
   
 
 0.945
JAK3
Tyrosine-protein kinase.
   
 
 0.934
IL23R
Interleukin-23 receptor.
   
 
 0.911
IL4R
Interleukin-4 receptor subunit alpha isoform X1.
  
  
 0.872
IL22RA1
Interleukin-22 receptor subunit alpha-1-like.
  
  
 0.870
LOC102743476
Leukemia inhibitory factor receptor-like.
  
  
  0.862
IL4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.
   
  
 0.855
IL6
Interleukin-6 isoform X1.
   
  
 0.855
LOC102733973
Interleukin-5 receptor subunit alpha-like.
  
  
  0.846
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.