STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAT1Proto-oncogene FRAT1. (168 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.
    
 0.999
DVL1
Segment polarity protein dishevelled homolog DVL-1 isoform X1.
    
 0.897
GSK3A
Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.
    
 0.878
DVL2
Segment polarity protein dishevelled homolog DVL-2 isoform X1.
    
 0.860
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.839
OGFRL1
Opioid growth factor receptor-like protein 1.
    
 0.828
PORCN
Protein-cysteine N-palmitoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family.
      
 0.630
LOC102745156
Catenin beta-1-like isoform X1.
     
 0.605
AXIN1
Axin-1 isoform X1.
    
 0.600
MAP3K4
Mitogen-activated protein kinase kinase kinase 4 isoform X1.
      
 0.578
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.