RAD17 protein (Leptonychotes weddellii) - STRING interaction network

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Predicted Interactions

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Score

RAD17

Cell cycle checkpoint protein RAD17. (634 aa)

Predicted Functional Partners:

RFC3

0.999

RFC4

0.999

RFC2

0.999

RFC5

0.999

HUS1

0.995

RAD9A

0.991

RAD1

0.977

ANKRD32

0.932

ATM

0.911

ATRIP

0.908

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD32	ATM	A0A2U3YGB4	A0A2U3YJR1	Ankyrin repeat domain-containing protein 32 isoform X1.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.895
ANKRD32	ATRIP	A0A2U3YGB4	A0A2U3Z414	Ankyrin repeat domain-containing protein 32 isoform X1.	ATR-interacting protein.	0.935
ANKRD32	HUS1	A0A2U3YGB4	A0A2U3XLU3	Ankyrin repeat domain-containing protein 32 isoform X1.	Checkpoint protein; Belongs to the HUS1 family.	0.915
ANKRD32	RAD1	A0A2U3YGB4	A0A2U3XW20	Ankyrin repeat domain-containing protein 32 isoform X1.	Cell cycle checkpoint protein RAD1.	0.922
ANKRD32	RAD17	A0A2U3YGB4	A0A2U3Y5E1	Ankyrin repeat domain-containing protein 32 isoform X1.	Cell cycle checkpoint protein RAD17.	0.932
ANKRD32	RAD9A	A0A2U3YGB4	A0A2U3Z057	Ankyrin repeat domain-containing protein 32 isoform X1.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.995
ANKRD32	RFC2	A0A2U3YGB4	A0A2U3YR32	Ankyrin repeat domain-containing protein 32 isoform X1.	Replication factor C subunit 2 isoform X1.	0.891
ANKRD32	RFC3	A0A2U3YGB4	A0A2U3XC21	Ankyrin repeat domain-containing protein 32 isoform X1.	Replication factor C subunit 3.	0.888
ANKRD32	RFC4	A0A2U3YGB4	A0A2U3YHT9	Ankyrin repeat domain-containing protein 32 isoform X1.	Replication factor C subunit 4.	0.921
ANKRD32	RFC5	A0A2U3YGB4	A0A2U3Z142	Ankyrin repeat domain-containing protein 32 isoform X1.	Replication factor C subunit 5 isoform X1.	0.887
ATM	ANKRD32	A0A2U3YJR1	A0A2U3YGB4	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Ankyrin repeat domain-containing protein 32 isoform X1.	0.895
ATM	ATRIP	A0A2U3YJR1	A0A2U3Z414	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATR-interacting protein.	0.883
ATM	HUS1	A0A2U3YJR1	A0A2U3XLU3	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Checkpoint protein; Belongs to the HUS1 family.	0.805
ATM	RAD1	A0A2U3YJR1	A0A2U3XW20	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint protein RAD1.	0.861
ATM	RAD17	A0A2U3YJR1	A0A2U3Y5E1	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint protein RAD17.	0.911
ATM	RAD9A	A0A2U3YJR1	A0A2U3Z057	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.912
ATM	RFC2	A0A2U3YJR1	A0A2U3YR32	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 2 isoform X1.	0.735
ATM	RFC3	A0A2U3YJR1	A0A2U3XC21	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 3.	0.671
ATM	RFC4	A0A2U3YJR1	A0A2U3YHT9	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 4.	0.713
ATM	RFC5	A0A2U3YJR1	A0A2U3Z142	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 5 isoform X1.	0.664