STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (415 aa)    
Predicted Functional Partners:
LOC102732990
Histone H2A; Belongs to the histone H2A family.
   
 0.891
SIN3B
Paired amphipathic helix protein Sin3b.
   
 0.886
HDAC9
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
  
 
0.864
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3.
    
 0.851
LOC102726804
Histone H2B; Belongs to the histone H2B family.
    
 0.840
LOC102738587
Histone H2B subacrosomal variant-like; Belongs to the histone H2B family.
    
 0.838
LOC102730207
Histone H2A; Belongs to the histone H2A family.
    
 0.835
LOC102742187
Histone H2B; Belongs to the histone H2B family.
    
 0.833
LEO1
RNA polymerase-associated protein LEO1.
   
 0.827
MTA2
Metastasis-associated protein MTA2 isoform X1.
    
 0.826
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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