PTPRE protein (Leptonychotes weddellii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PTPRE

Receptor-type tyrosine-protein phosphatase. (642 aa)

Predicted Functional Partners:

LRFN5

0.742

LOC102728967

0.709

KAZN

0.695

PTK7

0.685

IL1RAPL2

0.634

LRRC24

0.629

LRIT3

0.624

LRIT1

0.624

CALHM3

0.614

PTPN11

0.596

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALHM3	PTPRE	A0A2U3Y715	A0A2U3YCT3	Calcium homeostasis modulator protein 3.	Receptor-type tyrosine-protein phosphatase.	0.614
IL1RAPL2	PTK7	A0A2U3XMQ6	A0A2U3XZD5	X-linked interleukin-1 receptor accessory protein-like 2.	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.466
IL1RAPL2	PTPRE	A0A2U3XMQ6	A0A2U3YCT3	X-linked interleukin-1 receptor accessory protein-like 2.	Receptor-type tyrosine-protein phosphatase.	0.634
KAZN	PTPRE	A0A2U3YS43	A0A2U3YCT3	Kazrin-like.	Receptor-type tyrosine-protein phosphatase.	0.695
LOC102728967	LRFN5	A0A2U3YL28	A0A2U3X6R6	Interleukin-1 receptor accessory protein-like 1-like.	Leucine-rich repeat and fibronectin type-III domain-containing protein 5-like.	0.642
LOC102728967	PTK7	A0A2U3YL28	A0A2U3XZD5	Interleukin-1 receptor accessory protein-like 1-like.	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.466
LOC102728967	PTPRE	A0A2U3YL28	A0A2U3YCT3	Interleukin-1 receptor accessory protein-like 1-like.	Receptor-type tyrosine-protein phosphatase.	0.709
LRFN5	LOC102728967	A0A2U3X6R6	A0A2U3YL28	Leucine-rich repeat and fibronectin type-III domain-containing protein 5-like.	Interleukin-1 receptor accessory protein-like 1-like.	0.642
LRFN5	PTPRE	A0A2U3X6R6	A0A2U3YCT3	Leucine-rich repeat and fibronectin type-III domain-containing protein 5-like.	Receptor-type tyrosine-protein phosphatase.	0.742
LRIT1	LRIT3	A0A2U3YH43	A0A2U3X701	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1.	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.	0.569
LRIT1	PTK7	A0A2U3YH43	A0A2U3XZD5	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1.	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.932
LRIT1	PTPRE	A0A2U3YH43	A0A2U3YCT3	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1.	Receptor-type tyrosine-protein phosphatase.	0.624
LRIT3	LRIT1	A0A2U3X701	A0A2U3YH43	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1.	0.569
LRIT3	PTK7	A0A2U3X701	A0A2U3XZD5	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.932
LRIT3	PTPRE	A0A2U3X701	A0A2U3YCT3	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.	Receptor-type tyrosine-protein phosphatase.	0.624
LRRC24	PTPRE	A0A2U3YMM1	A0A2U3YCT3	Leucine-rich repeat-containing protein 24.	Receptor-type tyrosine-protein phosphatase.	0.629
PTK7	IL1RAPL2	A0A2U3XZD5	A0A2U3XMQ6	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	X-linked interleukin-1 receptor accessory protein-like 2.	0.466
PTK7	LOC102728967	A0A2U3XZD5	A0A2U3YL28	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Interleukin-1 receptor accessory protein-like 1-like.	0.466
PTK7	LRIT1	A0A2U3XZD5	A0A2U3YH43	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1.	0.932
PTK7	LRIT3	A0A2U3XZD5	A0A2U3X701	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3.	0.932