STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CENPJCentromere protein J. (1354 aa)    
Predicted Functional Partners:
ITSN2
Intersectin-2.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.971
SASS6
Spindle assembly abnormal protein 6 homolog.
   
 
 0.817
ENTHD1
ENTH domain-containing protein 1.
   
 0.809
AP2A1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.801
CEP152
Centrosomal protein of 152 kDa isoform X1.
   
 
 0.792
LOC102737850
Centrosomal protein of 63 kDa-like.
      
 0.769
ASPM
Abnormal spindle-like microcephaly-associated protein homolog isoform X1.
   
  
 0.717
PLK4
Serine/threonine-protein kinase PLK4 isoform X1.
   
 0.705
PLK2
Serine/threonine-protein kinase PLK2; Belongs to the protein kinase superfamily.
   
 0.700
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.