STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYBA2Beta-crystallin A2 isoform X1; Belongs to the beta/gamma-crystallin family. (197 aa)    
Predicted Functional Partners:
CRYAA
Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
  
 0.912
LOC102726777
Cyclin-dependent kinase 5 activator 2-like.
      
 0.695
MAK16
Protein MAK16 homolog; Belongs to the MAK16 family.
      
 0.678
LOC102746003
Clusterin-associated protein 1-like.
      
 0.676
LOC102740873
Beta-crystallin B2-like; Belongs to the beta/gamma-crystallin family.
  
  
0.579
CRYBA1
Beta-crystallin A3 isoform X1; Belongs to the beta/gamma-crystallin family.
  
  
0.543
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.539
CRYAB
Alpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
  
 0.499
GABRB3
Gamma-aminobutyric acid receptor subunit beta-3-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.491
USP26
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
      
 0.489
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.