STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFIT1BInterferon-induced protein with tetratricopeptide repeats 1B. (539 aa)    
Predicted Functional Partners:
EIF2AK2
Interferon-induced, double-stranded RNA-activated protein kinase.
   
 0.889
LEO1
RNA polymerase-associated protein LEO1.
    
 0.859
ISG15
Ubiquitin-like protein ISG15.
   
 0.829
LOC102741681
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
 0.814
EIF2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1.
   
  0.797
IFIT1
Interferon-induced protein with tetratricopeptide repeats 1.
  
  
 
0.791
LOC102728857
Probable ATP-dependent RNA helicase DDX58-like.
   
 0.777
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
 
 0.751
USP18
Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family.
   
 0.739
IFI44
LOW QUALITY PROTEIN: interferon-induced protein 44.
   
  
 0.709
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.