TCF3 protein (Leptonychotes weddellii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

TCF3

Transcription factor E2-alpha isoform X1. (654 aa)

Predicted Functional Partners:

ID1

0.999

LOC102745156

0.922

LYL1

0.902

MYOD1

0.854

MYOG

0.839

MYF5

0.759

ID2

0.709

LDB2

0.683

ASCL2

0.682

CREBBP

0.641

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL2	TCF3	A0A2U3Z2E6	A0A2U3YQK4	Achaete-scute homolog 2.	Transcription factor E2-alpha isoform X1.	0.682
CREBBP	LOC102745156	A0A2U3YT32	A0A2U3Y172	CREB-binding protein-like.	Catenin beta-1-like isoform X1.	0.994
CREBBP	MYF5	A0A2U3YT32	A0A2U3XU80	CREB-binding protein-like.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.410
CREBBP	MYOD1	A0A2U3YT32	A0A2U3Z4X5	CREB-binding protein-like.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.625
CREBBP	TCF3	A0A2U3YT32	A0A2U3YQK4	CREB-binding protein-like.	Transcription factor E2-alpha isoform X1.	0.641
ID1	ID2	A0A2U3X889	A0A2U3YMP3	DNA-binding protein inhibitor ID-1.	DNA-binding protein inhibitor ID-2 isoform X2.	0.841
ID1	MYF5	A0A2U3X889	A0A2U3XU80	DNA-binding protein inhibitor ID-1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.446
ID1	MYOD1	A0A2U3X889	A0A2U3Z4X5	DNA-binding protein inhibitor ID-1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.723
ID1	TCF3	A0A2U3X889	A0A2U3YQK4	DNA-binding protein inhibitor ID-1.	Transcription factor E2-alpha isoform X1.	0.999
ID2	ID1	A0A2U3YMP3	A0A2U3X889	DNA-binding protein inhibitor ID-2 isoform X2.	DNA-binding protein inhibitor ID-1.	0.841
ID2	MYOG	A0A2U3YMP3	A0A2U3XJX0	DNA-binding protein inhibitor ID-2 isoform X2.	Myogenin.	0.603
ID2	TCF3	A0A2U3YMP3	A0A2U3YQK4	DNA-binding protein inhibitor ID-2 isoform X2.	Transcription factor E2-alpha isoform X1.	0.709
LDB2	LYL1	A0A2U3YI83	A0A2U3XGN0	LIM domain-binding protein 2-like isoform X1.	Protein lyl-1.	0.610
LDB2	TCF3	A0A2U3YI83	A0A2U3YQK4	LIM domain-binding protein 2-like isoform X1.	Transcription factor E2-alpha isoform X1.	0.683
LOC102745156	CREBBP	A0A2U3Y172	A0A2U3YT32	Catenin beta-1-like isoform X1.	CREB-binding protein-like.	0.994
LOC102745156	MYOD1	A0A2U3Y172	A0A2U3Z4X5	Catenin beta-1-like isoform X1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.473
LOC102745156	TCF3	A0A2U3Y172	A0A2U3YQK4	Catenin beta-1-like isoform X1.	Transcription factor E2-alpha isoform X1.	0.922
LYL1	LDB2	A0A2U3XGN0	A0A2U3YI83	Protein lyl-1.	LIM domain-binding protein 2-like isoform X1.	0.610
LYL1	TCF3	A0A2U3XGN0	A0A2U3YQK4	Protein lyl-1.	Transcription factor E2-alpha isoform X1.	0.902
MYF5	CREBBP	A0A2U3XU80	A0A2U3YT32	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	CREB-binding protein-like.	0.410