STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP14Matrix metalloproteinase-14. (582 aa)    
Predicted Functional Partners:
LOC102743592
Metalloproteinase inhibitor 2-like.
    
 0.999
TIMP1
Metalloproteinase inhibitor 1.
   
 0.958
MMP13
Collagenase 3.
  
0.932
LOC102727675
Decorin; May affect the rate of fibrils formation.
     
 0.931
HBEGF
Proheparin-binding EGF-like growth factor.
    
 0.897
MMP16
Matrix metalloproteinase-16.
  
  
0.799
LOC102726697
Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1.
     
 0.791
GNAI2
Guanine nucleotide-binding protein G(I) subunit alpha-2.
     
 0.791
RDX
Radixin isoform X1.
    
 
 0.774
APOA1
Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.
    
   0.771
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.