TSG101 protein (Leptonychotes weddellii) - STRING interaction network

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Score

TSG101

Tumor susceptibility gene 101 protein isoform X1. (391 aa)

Predicted Functional Partners:

CD63

0.999

VPS28

0.999

HGS

0.993

MVB12A

0.984

MVB12B

0.979

VPS37A

0.965

UBA52

0.959

CD9

0.951

PDCD6IP

0.950

VPS37C

0.924

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD63	CD9	A0A2U3XBE4	A0A2U3XX36	Tetraspanin.	Tetraspanin.	0.706
CD63	PDCD6IP	A0A2U3XBE4	A0A2U3XW84	Tetraspanin.	Programmed cell death 6-interacting protein-like isoform X1.	0.489
CD63	TSG101	A0A2U3XBE4	A0A2U3YST3	Tetraspanin.	Tumor susceptibility gene 101 protein isoform X1.	0.999
CD63	VPS28	A0A2U3XBE4	A0A2U3YRL9	Tetraspanin.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.473
CD9	CD63	A0A2U3XX36	A0A2U3XBE4	Tetraspanin.	Tetraspanin.	0.706
CD9	PDCD6IP	A0A2U3XX36	A0A2U3XW84	Tetraspanin.	Programmed cell death 6-interacting protein-like isoform X1.	0.491
CD9	TSG101	A0A2U3XX36	A0A2U3YST3	Tetraspanin.	Tumor susceptibility gene 101 protein isoform X1.	0.951
HGS	MVB12A	A0A2U3YHE0	A0A2U3YUB1	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12A.	0.607
HGS	MVB12B	A0A2U3YHE0	A0A2U3YTP2	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12B-like.	0.640
HGS	PDCD6IP	A0A2U3YHE0	A0A2U3XW84	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Programmed cell death 6-interacting protein-like isoform X1.	0.562
HGS	TSG101	A0A2U3YHE0	A0A2U3YST3	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Tumor susceptibility gene 101 protein isoform X1.	0.993
HGS	UBA52	A0A2U3YHE0	A0A2U3YV30	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	ubiquitin-60S ribosomal protein L40 isoform X3.	0.834
HGS	VPS28	A0A2U3YHE0	A0A2U3YRL9	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.790
HGS	VPS37A	A0A2U3YHE0	A0A2U3YMT7	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 37A isoform X1.	0.625
HGS	VPS37C	A0A2U3YHE0	A0A2U3XFW1	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 37C.	0.638
MVB12A	HGS	A0A2U3YUB1	A0A2U3YHE0	Multivesicular body subunit 12A.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.607
MVB12A	MVB12B	A0A2U3YUB1	A0A2U3YTP2	Multivesicular body subunit 12A.	Multivesicular body subunit 12B-like.	0.935
MVB12A	PDCD6IP	A0A2U3YUB1	A0A2U3XW84	Multivesicular body subunit 12A.	Programmed cell death 6-interacting protein-like isoform X1.	0.943
MVB12A	TSG101	A0A2U3YUB1	A0A2U3YST3	Multivesicular body subunit 12A.	Tumor susceptibility gene 101 protein isoform X1.	0.984
MVB12A	VPS28	A0A2U3YUB1	A0A2U3YRL9	Multivesicular body subunit 12A.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.994