STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CETN2Centrin-2. (187 aa)    
Predicted Functional Partners:
LOC102732536
DNA repair protein complementing XP-C cells-like.
    
 0.999
PLK1
Serine/threonine-protein kinase PLK.
     
 0.978
RAD23A
UV excision repair protein RAD23 homolog A isoform X1.
   
 0.929
LOC102749246
Ubiquitin-conjugating enzyme E2 variant 1-like isoform X2.
   
 
 0.847
DDB2
DNA damage-binding protein 2 isoform X1.
   
 0.838
ARL13B
ADP-ribosylation factor-like protein 13B isoform X1.
    
 0.826
DDB1
DNA damage-binding protein 1.
     
 0.812
LOC102728667
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]
   
 
 0.807
XPA
DNA repair protein complementing XP-A cells.
     
 0.801
NIN
Ninein isoform X1.
    
 
 0.795
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.