STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNAR1Interferon alpha/beta receptor 1. (560 aa)    
Predicted Functional Partners:
TYK2
Non-receptor tyrosine-protein kinase TYK2-like.
   
 0.999
IFNB1
Interferon beta.
   
 0.994
LOC102749847
Tyrosine-protein kinase JAK1-like.
   
 0.992
STAT2
Signal transducer and activator of transcription.
   
 0.983
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
     
 0.969
IFNE
Interferon epsilon.
   
 0.969
JAK2
Tyrosine-protein kinase.
   
 0.954
IFNK
Interferon kappa.
   
 0.952
IL10
Interleukin-10.
    
 0.951
IFNGR2
Interferon gamma receptor 2.
   
 
 0.944
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.