STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102731850Tyrosine-protein kinase receptor. (757 aa)    
Predicted Functional Partners:
IRS1
Insulin receptor substrate 1-like isoform X1.
    
 0.960
IGF2
Insulin-like growth factor II.
    
 0.960
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.957
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.924
GRB10
Growth factor receptor-bound protein 10.
    
 0.922
LOC102737030
Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.908
IGF1R
Insulin-like growth factor 1 receptor-like.
 
      0.900
LOC102749673
Insulin-like growth factor 1 receptor-like.
 
      0.900
LOC102745156
Catenin beta-1-like isoform X1.
    
 0.892
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.891
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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