EDEM1 protein (Leptonychotes weddellii) - STRING interaction network

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Score

EDEM1

alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (361 aa)

Predicted Functional Partners:

LOC102728367

0.925

EDEM3

0.829

CANX

0.680

DNAJB9

0.644

DERL1

0.562

ERO1LB

0.548

LOC102747329

0.536

PDIA4

0.530

DNAJC3

0.529

HSPA5

0.529

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CANX	DERL1	A0A2U3Y8B6	A0A2U3YXE2	Calnexin isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.422
CANX	EDEM1	A0A2U3Y8B6	A0A2U3Z590	Calnexin isoform X1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.680
CANX	EDEM3	A0A2U3Y8B6	A0A2U3XNB4	Calnexin isoform X1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.412
CANX	ERO1LB	A0A2U3Y8B6	A0A2U3YR05	Calnexin isoform X1.	ERO1-like protein beta.	0.511
CANX	HSPA5	A0A2U3Y8B6	A0A2U3YKM0	Calnexin isoform X1.	78 kDa glucose-regulated protein isoform X2; Belongs to the heat shock protein 70 family.	0.979
CANX	LOC102728367	A0A2U3Y8B6	A0A2U3YQQ9	Calnexin isoform X1.	ER degradation-enhancing alpha-mannosidase-like protein 1-like.	0.680
CANX	PDIA4	A0A2U3Y8B6	A0A2U3XHJ0	Calnexin isoform X1.	Protein disulfide-isomerase A4.	0.785
DERL1	CANX	A0A2U3YXE2	A0A2U3Y8B6	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Calnexin isoform X1.	0.422
DERL1	DNAJB9	A0A2U3YXE2	A0A2U3XLQ3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	dnaJ homolog subfamily B member 9 isoform X1.	0.404
DERL1	DNAJC3	A0A2U3YXE2	A0A2U3XQK8	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	dnaJ homolog subfamily C member 3.	0.559
DERL1	EDEM1	A0A2U3YXE2	A0A2U3Z590	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.562
DERL1	EDEM3	A0A2U3YXE2	A0A2U3XNB4	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.489
DERL1	HSPA5	A0A2U3YXE2	A0A2U3YKM0	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	78 kDa glucose-regulated protein isoform X2; Belongs to the heat shock protein 70 family.	0.968
DERL1	LOC102728367	A0A2U3YXE2	A0A2U3YQQ9	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER degradation-enhancing alpha-mannosidase-like protein 1-like.	0.562
DNAJB9	DERL1	A0A2U3XLQ3	A0A2U3YXE2	dnaJ homolog subfamily B member 9 isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.404
DNAJB9	DNAJC3	A0A2U3XLQ3	A0A2U3XQK8	dnaJ homolog subfamily B member 9 isoform X1.	dnaJ homolog subfamily C member 3.	0.700
DNAJB9	EDEM1	A0A2U3XLQ3	A0A2U3Z590	dnaJ homolog subfamily B member 9 isoform X1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.644
DNAJB9	EDEM3	A0A2U3XLQ3	A0A2U3XNB4	dnaJ homolog subfamily B member 9 isoform X1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.495
DNAJB9	HSPA5	A0A2U3XLQ3	A0A2U3YKM0	dnaJ homolog subfamily B member 9 isoform X1.	78 kDa glucose-regulated protein isoform X2; Belongs to the heat shock protein 70 family.	0.895
DNAJB9	LOC102728367	A0A2U3XLQ3	A0A2U3YQQ9	dnaJ homolog subfamily B member 9 isoform X1.	ER degradation-enhancing alpha-mannosidase-like protein 1-like.	0.644