STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)    
Predicted Functional Partners:
HDAC5
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
    
 0.830
HDAC4
Histone deacetylase 4-like.
    
 0.830
HDAC3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.828
HDAC7
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
    
 0.826
HDAC9
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
    
 0.824
HDAC8
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.824
HDAC1
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.817
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.817
LEO1
RNA polymerase-associated protein LEO1.
    
 0.777
KDM6B
Lysine-specific demethylase 6B.
    
 0.746
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.