STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIE1Tyrosine-protein kinase receptor Tie-1. (1015 aa)    
Predicted Functional Partners:
LOC102740880
Nitric oxide synthase, endothelial-like.
   
  
 0.969
ANGPT1
Angiopoietin-1 isoform X1.
   
 0.920
ANGPT2
Angiopoietin-2 isoform X1.
   
 0.917
LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1.
   
 
0.862
ANGPT4
Angiopoietin-4.
   
 0.792
FGF2
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.713
VEGFB
Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family.
    
 0.712
LOC102740157
Cadherin-5-like; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.708
PDGFC
Platelet-derived growth factor C-like; Belongs to the PDGF/VEGF growth factor family.
    
 0.701
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.696
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.