STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIF1ANHypoxia-inducible factor 1-alpha inhibitor. (349 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia-inducible factor 1-alpha isoform X1.
    
 0.997
EPAS1
Endothelial PAS domain-containing protein 1.
    
 0.963
HIF3A
Hypoxia-inducible factor 3-alpha isoform X1.
    
 0.897
TNKS
Poly [ADP-ribose] polymerase.
    
 
 0.781
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
   0.771
PPP1R13L
relA-associated inhibitor.
    
   0.771
IL10RB
Interleukin-10 receptor subunit beta.
    
   0.693
FITM2
Fat storage-inducing transmembrane protein 2.
      
 0.647
FITM1
Fat storage-inducing transmembrane protein 1.
      
 0.627
CDYL
Chromodomain Y-like protein-like.
   
  
 0.585
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.