STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102737969Histone H2A; Belongs to the histone H2A family. (66 aa)    
Predicted Functional Partners:
KDM6B
Lysine-specific demethylase 6B.
    
 0.683
LOC102726286
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.653
LOC102746084
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.653
LOC102725568
Histone H2B; Belongs to the histone H2B family.
  
 0.622
LOC102728431
Histone H2B; Belongs to the histone H2B family.
  
 0.620
LOC102750992
Histone H2B; Belongs to the histone H2B family.
  
 0.620
LOC102746847
Histone H2B; Belongs to the histone H2B family.
  
 0.618
LOC102742187
Histone H2B; Belongs to the histone H2B family.
  
 0.612
LOC102744317
Histone H2B; Belongs to the histone H2B family.
  
 0.612
LOC102726804
Histone H2B; Belongs to the histone H2B family.
  
 0.612
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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