STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102745644Heparin cofactor 2-like isoform X1; Belongs to the serpin family. (296 aa)    
Predicted Functional Partners:
SERPIND1
Heparin cofactor 2; Belongs to the serpin family.
 
     0.948
LOC102744421
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.892
F13B
Coagulation factor XIII B chain.
   
 
 0.779
FGB
Fibrinogen beta chain isoform X1.
   
 0.746
SERPINC1
antithrombin-III; Belongs to the serpin family.
  
 
0.743
FGG
Fibrinogen gamma chain isoform X1.
   
 0.728
LOC102748009
Serpin B11-like; Belongs to the serpin family.
 
 
  0.661
LOC102735161
Corticosteroid-binding globulin-like; Belongs to the serpin family.
  
 
  0.630
APOH
Beta-2-glycoprotein 1.
   
 0.623
F9
Coagulation factor IX isoform X1.
   
 0.612
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.