STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTRB1LOW QUALITY PROTEIN: chymotrypsinogen B1; Belongs to the peptidase S1 family. (285 aa)    
Predicted Functional Partners:
APP
Amyloid beta A4 protein.
 
  
 0.888
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 0.873
LOC102741273
Ovochymase-1-like; Belongs to the peptidase S1 family.
 
  
 
0.861
CELA3B
Chymotrypsin-like elastase family member 3B isoform X2; Belongs to the peptidase S1 family.
  
   
0.844
CTRL
LOW QUALITY PROTEIN: chymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family.
  
   
0.838
LOC102738811
Anionic trypsin-like; Belongs to the peptidase S1 family.
  
0.803
LOC102739415
Cationic trypsin-like; Belongs to the peptidase S1 family.
  
0.802
LOC102744421
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
  
0.792
CLPS
Colipase isoform X1.
   
  
 0.769
MMP9
Matrix metalloproteinase-9.
    
 0.691
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.