| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C821_00152 | C821_00253 | C821_00152 | C821_00253 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.816 |
| C821_00152 | C821_00790 | C821_00152 | C821_00790 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA topoisomerase I. | 0.863 |
| C821_00152 | C821_00791 | C821_00152 | C821_00791 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA topoisomerase I. | 0.863 |
| C821_00152 | C821_00821 | C821_00152 | C821_00821 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, alpha subunit. | 0.680 |
| C821_00152 | dnaX | C821_00152 | C821_01369 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.714 |
| C821_00152 | priA | C821_00152 | C821_01589 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.456 |
| C821_00249 | C821_00253 | C821_00249 | C821_00253 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.861 |
| C821_00249 | C821_00790 | C821_00249 | C821_00790 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase I. | 0.628 |
| C821_00249 | C821_00791 | C821_00249 | C821_00791 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase I. | 0.628 |
| C821_00249 | C821_00821 | C821_00249 | C821_00821 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, alpha subunit. | 0.819 |
| C821_00249 | dnaX | C821_00249 | C821_01369 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.896 |
| C821_00249 | priA | C821_00249 | C821_01589 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.752 |
| C821_00249 | rplI | C821_00249 | C821_00250 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.858 |
| C821_00249 | rpsF | C821_00249 | C821_00254 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.434 |
| C821_00249 | rpsR | C821_00249 | C821_00252 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.556 |
| C821_00253 | C821_00152 | C821_00253 | C821_00152 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.816 |
| C821_00253 | C821_00249 | C821_00253 | C821_00249 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.861 |
| C821_00253 | C821_00790 | C821_00253 | C821_00790 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I. | 0.955 |
| C821_00253 | C821_00791 | C821_00253 | C821_00791 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I. | 0.955 |
| C821_00253 | C821_00821 | C821_00253 | C821_00821 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III, alpha subunit. | 0.946 |