| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C821_00149 | C821_00498 | C821_00149 | C821_00498 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ArsR family transcriptional regulator. | 0.414 |
| C821_00149 | C821_00915 | C821_00149 | C821_00915 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ADP-ribose pyrophosphatase. | 0.464 |
| C821_00149 | nadK | C821_00149 | C821_01245 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.489 |
| C821_00495 | C821_00497 | C821_00495 | C821_00497 | DeoR family transcriptional regulator, fructose operon transcriptional repressor. | PTS system, Fru family, IIC component. | 0.985 |
| C821_00495 | C821_00498 | C821_00495 | C821_00498 | DeoR family transcriptional regulator, fructose operon transcriptional repressor. | ArsR family transcriptional regulator. | 0.405 |
| C821_00497 | C821_00495 | C821_00497 | C821_00495 | PTS system, Fru family, IIC component. | DeoR family transcriptional regulator, fructose operon transcriptional repressor. | 0.985 |
| C821_00497 | C821_00498 | C821_00497 | C821_00498 | PTS system, Fru family, IIC component. | ArsR family transcriptional regulator. | 0.427 |
| C821_00498 | C821_00149 | C821_00498 | C821_00149 | ArsR family transcriptional regulator. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.414 |
| C821_00498 | C821_00495 | C821_00498 | C821_00495 | ArsR family transcriptional regulator. | DeoR family transcriptional regulator, fructose operon transcriptional repressor. | 0.405 |
| C821_00498 | C821_00497 | C821_00498 | C821_00497 | ArsR family transcriptional regulator. | PTS system, Fru family, IIC component. | 0.427 |
| C821_00498 | C821_00499 | C821_00498 | C821_00499 | ArsR family transcriptional regulator. | Zinc/manganese transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. | 0.485 |
| C821_00498 | C821_00500 | C821_00498 | C821_00500 | ArsR family transcriptional regulator. | Zinc/manganese transport system ATP-binding protein. | 0.423 |
| C821_00498 | C821_00501 | C821_00498 | C821_00501 | ArsR family transcriptional regulator. | Zinc/manganese transport system permease. | 0.423 |
| C821_00498 | C821_00915 | C821_00498 | C821_00915 | ArsR family transcriptional regulator. | ADP-ribose pyrophosphatase. | 0.488 |
| C821_00498 | nadK | C821_00498 | C821_01245 | ArsR family transcriptional regulator. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.499 |
| C821_00498 | rpoA | C821_00498 | C821_01432 | ArsR family transcriptional regulator. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.440 |
| C821_00499 | C821_00498 | C821_00499 | C821_00498 | Zinc/manganese transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. | ArsR family transcriptional regulator. | 0.485 |
| C821_00499 | C821_00500 | C821_00499 | C821_00500 | Zinc/manganese transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. | Zinc/manganese transport system ATP-binding protein. | 0.999 |
| C821_00499 | C821_00501 | C821_00499 | C821_00501 | Zinc/manganese transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. | Zinc/manganese transport system permease. | 0.999 |
| C821_00500 | C821_00498 | C821_00500 | C821_00498 | Zinc/manganese transport system ATP-binding protein. | ArsR family transcriptional regulator. | 0.423 |