Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C821_00750Helicase-exonuclease AddAB, AddB subunit. (1099 aa)    
Predicted Functional Partners:
addA
Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.
 
 0.998
ruvA
Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.795
C821_00396
DNA helicase II/ATP-dependent DNA helicase PcrA.
    
 0.744
C821_00397
DNA helicase II/ATP-dependent DNA helicase PcrA.
    
 0.744
ruvB
Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
 0.715
C821_01294
Hypothetical protein.
  
     0.675
C821_00140
Hypothetical protein.
  
     0.644
C821_00879
Hypothetical protein.
  
     0.633
C821_01032
Hypothetical protein.
  
     0.626
C821_00748
Diphosphomevalonate decarboxylase.
       0.590
Your Current Organism:
Lactobacillus sp. ASF360
NCBI taxonomy Id: 97137
Other names: L. sp. ASF360
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