C821_00783 protein (Lactobacillus sp. ASF360)

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Score

C821_00783

DNA topoisomerase IV, B subunit. (645 aa)

Predicted Functional Partners:

parC

0.999

gyrA

0.995

C821_01173

0.731

C821_01174

0.731

C821_01180

0.731

recF

0.684

polA

0.679

fusA

0.667

truB

0.656

ileS

0.629

Your Current Organism:

Lactobacillus sp. ASF360

NCBI taxonomy Id: 97137
Other names: L. sp. ASF360

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C821_00783	C821_01173	C821_00783	C821_01173	DNA topoisomerase IV, B subunit.	Hypothetical protein.	0.731
C821_00783	C821_01174	C821_00783	C821_01174	DNA topoisomerase IV, B subunit.	Hypothetical protein.	0.731
C821_00783	C821_01180	C821_00783	C821_01180	DNA topoisomerase IV, B subunit.	Hypothetical protein.	0.731
C821_00783	fusA	C821_00783	C821_01460	DNA topoisomerase IV, B subunit.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.667
C821_00783	gyrA	C821_00783	C821_00255	DNA topoisomerase IV, B subunit.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.995
C821_00783	ileS	C821_00783	C821_00917	DNA topoisomerase IV, B subunit.	isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.	0.629
C821_00783	parC	C821_00783	C821_00782	DNA topoisomerase IV, B subunit.	DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.	0.999
C821_00783	polA	C821_00783	C821_01699	DNA topoisomerase IV, B subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.679
C821_00783	recF	C821_00783	C821_00257	DNA topoisomerase IV, B subunit.	DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.	0.684
C821_00783	truB	C821_00783	C821_00946	DNA topoisomerase IV, B subunit.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.656
C821_01173	C821_00783	C821_01173	C821_00783	Hypothetical protein.	DNA topoisomerase IV, B subunit.	0.731
C821_01173	C821_01174	C821_01173	C821_01174	Hypothetical protein.	Hypothetical protein.	0.966
C821_01174	C821_00783	C821_01174	C821_00783	Hypothetical protein.	DNA topoisomerase IV, B subunit.	0.731
C821_01174	C821_01173	C821_01174	C821_01173	Hypothetical protein.	Hypothetical protein.	0.966
C821_01174	C821_01180	C821_01174	C821_01180	Hypothetical protein.	Hypothetical protein.	0.760
C821_01180	C821_00783	C821_01180	C821_00783	Hypothetical protein.	DNA topoisomerase IV, B subunit.	0.731
C821_01180	C821_01174	C821_01180	C821_01174	Hypothetical protein.	Hypothetical protein.	0.760
fusA	C821_00783	C821_01460	C821_00783	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	DNA topoisomerase IV, B subunit.	0.667
fusA	gyrA	C821_01460	C821_00255	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.603
fusA	ileS	C821_01460	C821_00917	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.	0.823