STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
C821_00819
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.997
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.996
C821_01721
Fructose-1,6-bisphosphate aldolase, class II.
 
 
 0.993
C821_00496
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.973
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
    
 0.953
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.951
C821_00248
Fructokinase.
    
 0.950
C821_01063
Mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.950
eno
Enolase 3; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.941
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.902
Your Current Organism:
Lactobacillus sp. ASF360
NCBI taxonomy Id: 97137
Other names: L. sp. ASF360
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