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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C821_00899RecD/TraA family helicase. (510 aa)    
Predicted Functional Partners:
C821_00908
Exodeoxyribonuclease V alpha subunit.
 
     0.976
C821_00907
Hypothetical protein.
 
      0.900
C821_00259
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.824
addA
Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.
  
 
 0.820
C821_00790
DNA topoisomerase I.
   
 
 0.671
C821_00791
DNA topoisomerase I.
   
 
 0.671
C821_00396
DNA helicase II/ATP-dependent DNA helicase PcrA.
  
 
 0.659
C821_00397
DNA helicase II/ATP-dependent DNA helicase PcrA.
  
 
 0.659
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.579
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.567
Your Current Organism:
Lactobacillus sp. ASF360
NCBI taxonomy Id: 97137
Other names: L. sp. ASF360
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