| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C821_00403 | recX | C821_00403 | C821_01215 | YegS//BmrU family lipid kinase. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.601 |
| C821_01214 | C821_01216 | C821_01214 | C821_01216 | Hypothetical protein. | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.561 |
| C821_01214 | recX | C821_01214 | C821_01215 | Hypothetical protein. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.803 |
| C821_01216 | C821_01214 | C821_01216 | C821_01214 | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Hypothetical protein. | 0.561 |
| C821_01216 | recX | C821_01216 | C821_01215 | 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.631 |
| C821_01807 | dnaJ | C821_01807 | C821_00939 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.466 |
| C821_01807 | hrcA | C821_01807 | C821_00942 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.410 |
| C821_01807 | polA | C821_01807 | C821_01699 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.639 |
| C821_01807 | radA | C821_01807 | C821_01400 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.545 |
| C821_01807 | recA | C821_01807 | C821_01209 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.796 |
| C821_01807 | recO | C821_01807 | C821_00723 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA repair protein recO; Involved in DNA repair and RecF pathway recombination. | 0.454 |
| C821_01807 | recX | C821_01807 | C821_01215 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.696 |
| dnaJ | C821_01807 | C821_00939 | C821_01807 | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.466 |
| dnaJ | hrcA | C821_00939 | C821_00942 | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.968 |
| dnaJ | polA | C821_00939 | C821_01699 | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.663 |
| dnaJ | recA | C821_00939 | C821_01209 | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.757 |
| dnaJ | recX | C821_00939 | C821_01215 | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.559 |
| hrcA | C821_01807 | C821_00942 | C821_01807 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.410 |
| hrcA | dnaJ | C821_00942 | C821_00939 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Chaperone dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.968 |
| hrcA | recX | C821_00942 | C821_01215 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.593 |