| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C821_00771 | C821_00772 | C821_00771 | C821_00772 | Carbamoyl-phosphate synthase, small subunit. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
| C821_00771 | C821_01272 | C821_00771 | C821_01272 | Carbamoyl-phosphate synthase, small subunit. | Uracil-xanthine permease. | 0.826 |
| C821_00771 | C821_01621 | C821_00771 | C821_01621 | Carbamoyl-phosphate synthase, small subunit. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| C821_00771 | pyrC | C821_00771 | C821_01620 | Carbamoyl-phosphate synthase, small subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
| C821_00771 | pyrD | C821_00771 | C821_01624 | Carbamoyl-phosphate synthase, small subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.824 |
| C821_00771 | pyrE | C821_00771 | C821_01626 | Carbamoyl-phosphate synthase, small subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.771 |
| C821_00771 | pyrF | C821_00771 | C821_01625 | Carbamoyl-phosphate synthase, small subunit. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.939 |
| C821_00771 | pyrR | C821_00771 | C821_01271 | Carbamoyl-phosphate synthase, small subunit. | Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.626 |
| C821_00771 | pyrR-2 | C821_00771 | C821_01623 | Carbamoyl-phosphate synthase, small subunit. | pyrR protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.626 |
| C821_00772 | C821_00771 | C821_00772 | C821_00771 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit. | 0.999 |
| C821_00772 | C821_01272 | C821_00772 | C821_01272 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Uracil-xanthine permease. | 0.645 |
| C821_00772 | C821_01621 | C821_00772 | C821_01621 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.998 |
| C821_00772 | carA | C821_00772 | C821_01619 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
| C821_00772 | pyrC | C821_00772 | C821_01620 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.991 |
| C821_00772 | pyrD | C821_00772 | C821_01624 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.891 |
| C821_00772 | pyrE | C821_00772 | C821_01626 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.894 |
| C821_00772 | pyrF | C821_00772 | C821_01625 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.921 |
| C821_00772 | pyrR | C821_00772 | C821_01271 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.590 |
| C821_00772 | pyrR-2 | C821_00772 | C821_01623 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | pyrR protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.590 |
| C821_01272 | C821_00771 | C821_01272 | C821_00771 | Uracil-xanthine permease. | Carbamoyl-phosphate synthase, small subunit. | 0.826 |