STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (121 aa)    
Predicted Functional Partners:
C821_01299
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.747
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.679
C821_01488
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.639
C821_01300
Hypothetical protein.
       0.612
C821_00916
Cold shock protein (beta-ribbon, CspA family).
   
  
 0.560
C821_00098
CPA2 family monovalent cation:H+ antiporter-2; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.527
C821_00967
Cyclopropane-fatty-acyl-phospholipid synthase.
      
 0.521
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.503
C821_00346
Acetaldehyde dehydrogenase/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.494
C821_01660
Hypothetical protein.
     
 0.408
Your Current Organism:
Lactobacillus sp. ASF360
NCBI taxonomy Id: 97137
Other names: L. sp. ASF360
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.